LGR6 and polycystic ovary syndrome: In the present study swertiamarin could revert back mRNA expression of gonadotropin receptors, mRNA and protein expression of StAR, CYP11A1, CYP19A1, 17β-HSD and 3β-HSD, their enzyme activity along with secretion of the corresponding steroid hormones estradiol and progesterone in hLGC’s from PCOS-IR thus improving the process of steroidogenesis.