PIK3C3 and small cell lung carcinoma: The results showed that overexpression of METTL3 or knockdown of DCP2 in chemotherapy-sensitive SCLC cells increased the expression levels of Beclin 1 and Vps34, while knockdown of METTL3 or overexpression of DCP2 in chemotherapy-resistant SCLC cells significantly decreased the expression levels of Beclin 1 and Vps34 (Fig. S5A-D).