Lymphoma susceptibility is also associated with IL-18 (rs1946518) putatively through promoting proliferation and inhibiting apoptosis via unbalance of v-myc myelocytomatosis viral oncogene homolog (c-myc)/tumor protein p53 (TP53) and B-cell lymphoma-2 (Bcl-2)/Bcl-2-associated X protein (Bax) [128]. This evidence concerns the gene TP53 and lymphoma.