Although lesional macrophage content in both Ldlr−/−Diaph1−/− and Ldlr−/− mice was significantly correlated with atherosclerosis and plasma cholesterol and triglyceride concentrations, our analyses (Supplementary Table 8) probing specific roles for the Diaph1 genotype in Ldlr−/− mice suggested that DIAPH1 appears to exert negligible effects on the dependence of atherosclerotic lesion area on macrophage content. The gene discussed is LDLR; the disease is atherosclerosis.