Twenty-four genes were significantly highly expressed in tumor tissues (p < 0.05), including IFNG, CD8B, CXCR3, IFNB1, CD8A, P2RX7, PRF1, FOXP3, IL10, NLRP3, CASP1, CD4, LY96, ENTPD1, BAX, CASP8, IL17RA, NT5E, IL1B, IFNGR1, MYD88, TLR4, PDIA3, and CALR. The gene discussed is CASP8; the disease is neoplasm.