Body weight loss in ApcMin/+Clec7a−/− mice after DSS-treatment was significantly milder than that in ApcMin/+ mice (Fig. 1a), and at day 28 after DSS-treatment, polyp number in the colon was significantly reduced in ApcMin/+Clec7a−/− mice (Fig. 1b, c). Here, CLEC7A is linked to polyp.