The immunohistochemical tests had the following results: intense and diffuse positive nuclear reaction in 60% of the nuclei for Ki-67, intense and diffuse positive nuclear reaction in lipoblastic tumor cells for MDM2, intense and diffuse positive nuclear reaction in 90% of the nuclei (overexpression pattern) for p53, intense and diffuse positive nuclear reaction in tumor cells for p16, intense and diffuse cytoplasmic positive reaction in tumor cells for vimentin, and negative reaction for glial fibrillary acidic protein and smooth muscle actin. The gene discussed is TP53; the disease is neoplasm.