In addition, knockdown of CBS and CSE inhibits the PI3K‐Akt (PI3K, Akt, and pAkt), focal adhesion kinase‐paxillin, and Ras‐MAPK (Ras, Raf, ERK1/2, and pERK1/2) pathways,116 thus confirming the promoting effect of CBS and CSE on BC. The gene discussed is CTH; the disease is breast cancer.