Finally, COVID-19 vaccination and IVIg administration similarly led to a sustained decrease of CD32b expressing T cells (0.1 ± 0.1% vs. 16.4 ± 19.4%, p = 0.008) and non-classical monocytes (0% vs. 2.3 ± 3.1%, p = 0.03). The gene discussed is FCGR2B; the disease is COVID-19.