While SNCA point mutations or multiplications are rare, mutations in the gene for the leucine-rich repeat kinase-2 (LRRK2) were found to be a much more common cause of PD, accounting for 3–15% of familial cases, and for about 1–2% of seemingly “sporadic” cases in individuals of European descent (Zimprich et al. 2004). The gene discussed is LRRK2; the disease is Parkinson disease.