Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1), encoded by EIF4EBP1 gene, is a key substrate and downstream effector of the mechanistic target of rapamycin complex 1 (mTORC1), implicated in a variety of physiological and pathological processes including aging and cancer (Schalm et al., 2003; Weichhart, 2018). This evidence concerns the gene EIF4EBP1 and cancer.