Indeed, there was less vessel coverage and fewer vessels in NPCTKO GBMs than NSCHRas-shp53 GBMs, mirroring a previous study showing OLIG2+ gliomas had largely normal vasculature, but that vessel density, vessel size, and the vascular and luminal areas within OLIG2− gliomas were significantly increased (Griveau et al., 2018). The gene discussed is OLIG2; the disease is central nervous system cancer.