CD8A and neoplasm: mIF analyses revealed significantly higher densities of CD3+CD8+ tumor-infiltrating T lymphocytes (TILs) in the Nivo+CT arm (P = 0.032; Extended Data Fig. 8d) and, to a greater extent, in the Ipi+Nivo+CT arm (P = 0.005; Extended Data Fig. 8d) after neoadjuvant therapy.