Further, by applying major histocompatibility complex (MHC)-binding predictive algorithms to nonsynonymous single-nucleotide variations (SNVs) identified by exome sequencing data from two mouse MM cell lines, we identified potential neoantigens with high binding capacity to MHC class I and/or class II molecules, a fraction of which were functionally validated as having specific T cell immunogenicity (Extended Data Fig. 8g and Supplementary Table 9). Here, HLA-C is linked to Miyoshi myopathy.