Two of these mouse lines were termed MImb1 and MIcγ1 as they carry MYC and IKK2NF-κB expression by mb1-cre or cγ1-cre alleles, respectively, which indicates that NF-κB activation accelerated MYC-driven MM development in these two models compared to Vk*MYC mice (mOS, 197 d and 208 d versus 509 d; P < 0.001). The gene discussed is MYC; the disease is Miyoshi myopathy.