In the 1476 patients with old myocardial infarction (OMI) and glucose intolerance, we analyzed 415,328 combinations of factors of < 4 clinical parameters and identified 242 combinations of factors that predicted the occurrence of hospitalization and LAMP revealed that the use of proton pump inhibitors high plasma BNP levels, diuretics use, advanced age, and lack of anti-dyslipidemia drugs were linked to cardiovascular events, all of which were verified by independently drawn Kaplan–Meier curves, indicating that the determined factors accurately affected cardiovascular events10. The gene discussed is NPPB; the disease is metabolic syndrome.