In line with this, we found enrichment for ERGs (P value = 3.4 × 10−3; Methods and Supplementary Fig. 17), including the mesothelioma drivers NCOR2 and EZH2, among the genes highly expressed in CIMP-high tumors, and more generally in the list of MPM drivers (q value = 2.1 × 10−5). Here, EZH2 is linked to mesothelioma.