A total of 46.7% (14/30) of patients had tumors that were PD-L1 positive [tumor area positivity (TAP) ≥ 1% was defined as positive, proportion of tumor and/or immune cells with PD-L1 staining at any intensity].8 Representative cases with positive (cases 11, 23, and 30) and negative PD-L1 expression (case 18) are shown in Fig. 3a. The gene discussed is CD274; the disease is neoplasm.