CD8A and renal cell carcinoma: To confirm their cytotoxic potential, we co-cultured isolated tumor cells from resected RCC tumors with expanded autologous Vδ2− T cells, containing the PTT+ population, or αβ CD8+ tumor-infiltrating lymphoyctes (TILs), and quantitated killing through time-lapse microscopy (summarized in Extended Data Fig. 7).