TBK1 and cholangiocarcinoma: Moreover, correlation analyses showed that the expression of TBK1 correlated with the expression of E-cadherin (r = −0.3799, P < 0.001) and vimentin (r = 0.3818, P < 0.001) (Fig. 4I), suggesting that TBK1 is highly expressed mainly in mesenchymal phenotype cholangiocarcinoma tissues.