Substitution of the Pro residue in the GDPC motif by a leucine, as in the Ljsymrk-14 mutant (Kosuta et al. 2011), appears to abolish a proteolytic release of the malectin-like domain (MLD) fragment and impairs the epidermal infection process, although cortical and nodule primordium infection are apparently unaffected (Kosuta et al. 2011; Antolín-Llovera et al. 2014a; Li et al. 2018). Here, MLEC is linked to infection.