Age, menopausal status and CA125 levels were not statistically related to tumor origin, whereas women with non-ovarian tumors had significantly higher CEA levels (55.1 vs 5.8 ng/mL, p = 0.03) and significantly lower CA125/CEA ratios (38.3 vs. 333.5; p = 0.006). This evidence concerns the gene MUC16 and ovarian neoplasm.