FTH1 and acute myeloid leukemia: After assessing an NCOA4 effective knockdown and FTH1 increase in MOLM-14 and OCI-AML2 cells with two different inducible NCOA4 shRNA constructs (S 2c), we compared the DHA treatment effects in the shSCR (scrambled) or shRNA NCOA4 AML cell lines.