CD8A and neoplasm: Consistently, Rig-I knockdown greatly enhanced the capacity of OT-I CD8+ T cells to restrict B16-OVA tumor growth (Supplemental Figure 4D), and antigen-specific CD8+ T cell infiltration (Supplemental Figure 4E) and higher levels of CD107a and IFN-γ expression (Supplemental Figure 4F) were also detected.