The mean scores of healthy group were 0.95(SE: 0.08), 83.1(SE: 0.23), 25.1(SE: 0.20), followed by HIV/AIDS of 0.78 (SE: 0.23), 84.7(SE: 0.13), 25.7(SE:0.17), CHB of 0.78(SE: 0.23), 73.7(SE: 0.25), 23.7 (SE: 0.18), depression of 0.75 (SE: 0.27), 67.1 (SE: 0.34), 21.3(SE: 0.25) and GAD of 0.72 (SE: 0.30), 63.9 (SE: 0.37), 20.7(SE: 0.26). This evidence concerns the gene GAD1 and major depressive disorder.