Four molecular subtypes, namely luminal A, luminal B, HER2-positive and triple-negative breast cancer (TNBC), have been associated with different patterns of metastatic spread; bone metastases with luminal A and B subtypes, liver metastases with HER2-positive subtype, and brain and lung metastases with TNBC and HER2-positive subtypes [3–5]. Here, ERBB2 is linked to triple-negative breast carcinoma.