Increased mRNA and protein levels of PRKN were observed in juvenile HD fibroblasts (Q68 and Q86) (Aladdin et al., 2019), and PRKN colocalizes with mHTT inclusion bodies in the brain of mHTT-Q72 YAC72 mice and with both cytoplasmic and nuclear inclusions in human brain. The gene discussed is PRKN; the disease is Huntington disease.