In a logistic regression analysis with CI as the dependent variable, using the age of onset, current diagnosis of hypertension, baseline MoCA scores, MDS-UPDRS III scores, and APOE ε4 status as independent variables (Table 2), predictive accuracy was higher than for age alone (AUC 0.80 [95% CI 0.74–0.86] vs. 0.71 [0.64–0.77], p = 0.003; Figure 2). Here, APOE is linked to hypertensive disorder.