The results showed that the expression of hsa-miR-506-3p was significantly correlated with the formation of a paravertebral abscess (P=0.002); the expression of hsa-miR-543 was significantly associated with the rim osteosclerosis and sequestration (P=0.000; P=0.008); the expression of hsa-miR-195-5p was significantly correlated with the increase of CRP (P=0.002) (Table 3). This evidence concerns the gene CRP and osteosclerosis.