HLA-DRB1 and Parkinson disease: By including 3041 PD cases and 4318 controls, we found that HLA-DRB rs660895 was associated with PD risk negatively in all models (AM: OR[95%CI] = 0.80 [0.74, 0.87], p <0.00001; DM: OR[95%CI]= 0.79 [0.71, 0.87], p<0.00001; RM: OR[95%CI]=0.67[0.52-0.86], p=0.002).