CD163 and Cirrhosis: However, sCD163 and sMR plasma/serum levels have been associated with a variety of other diseases and infection conditions (Andersen et al., 2018; Suzuki et al., 2018; Gong et al., 2021; Arneth and Kraus, 2022; Davidsson et al., 2022) as shedding of CD163 and CD206 is associated with macrophage activation (Grønbæk et al., 2020; Nielsen et al., 2020) in general and does not specifically indicate immuneparesis in patients with cirrhosis.