The results showed that the cellular uptake of Lf‐LP‐C6 in U87‐MG cells was significantly higher than that of PEG‐LP‐C6 (p < 0.05), which indicated that Lf‐modified liposomes enhanced the cellular uptake of formulations through recognizing LfR on the surface of glioma cells by a receptor‐mediated endocytosis pathway.11, 49. Here, ITLN1 is linked to central nervous system cancer.