NLRP3 and Parkinson disease: Studies have shown that in PD animal models, different neurotoxins, such as LPS, ROT, 6‐OHDA, and 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) were able to activate NLRP3 inflammasome by direct or indirect means, which initiated the inflammatory cascade and thus caused a continuous inflammatory environment, and ultimately damaged DA neurons.50, 51