In nasopharyngeal carcinoma (NPC), METTL1/WDR4 and m7G tRNA modification enhance the EMT process of NPC cells through the WNT/β-catenin pathway to promote NPC progression, and METTL1 is linked to the chemosensitivity of NPC cells to cisplatin and docetaxel97. The gene discussed is METTL1; the disease is nasopharyngeal carcinoma.