AKT1 and schizophrenia: miR-106b-5p, an inflammation- and tumor-associated miRNA, was reported in both schizophrenia and BD studies, while miR-195-5p, miR-181b, miR-144-5p, miR-130b, and let-7g were documented in both schizophrenia and MDD subjects, indicating the pathological mechanisms of dysregulation of AKT pathway, cytokine production, macrophage polarization, energy metabolism in those disorders,68 thus providing a plausible explanation for the overlapping symptom spectrum across different mental disorders.