To have an overview of PXN expression, we first analyzed the expression of PXN in various cancers as shown in Fig. 1A. Of note, PXN mRNA expression was significantly higher in ovarian cancer tissue compared with that in normal ovary tissue in both GSE18520 and GSE27651 datasets (all P < 0.05) (Fig. 1B). The gene discussed is PXN; the disease is ovarian carcinoma.