NRXN2 and Anxiety: In the domain of repetitive behaviors, male, but not female, Nrxn2 KO mice exhibited increased nestlet shredding behavior without any impairments in other measures of repetitive behaviors including self-grooming, jumping and marbles buried; however, these findings were not accompanied by ASD-related associated symptoms including anxiety-like behavior and working memory deficits (Haile et al., 2022).