Our laboratory has previously reported on chlamydial modulation of focal adhesion kinase (FAK) (Thwaites et al., 2014; Pedrosa et al., 2020); given that FAK has been shown to antagonize Hippo-mediated YAP phosphorylation at S397 (Hu et al., 2017), infection may potentially impact YAP inhibition by Hippo in this way as well. This evidence concerns the gene YAP1 and infection.