NFKB1 and infection: However, the relevance of CPAF to NF-κB antagonism has been brought into question by new data, given that harvest of host protein lysates with more robust methods of CPAF inhibition did not result in p65 cleavage (Johnson et al., 2015), and infection with CPAF-deficient mutant strains does not exhibit increased NF-κB activation (Snavely et al., 2014).