The expression levels of ETS2, ETV4, ETV5, ETV2, ELK1, ETV3, ELF1, ELF4, ELF3, EHF and ETV7 were much higher in CRC than in nontumoral tissues, while ERG, FLI1, SPDEF, ELF2 and SPIB showed the opposite trends. The gene discussed is ELF3; the disease is colorectal carcinoma.