Furthermore, among all upregulated genes, the expression levels of ETS2, ETV4, ETV5, ETV2, ELK1, ETV3, ELF4, ELF3, EHF and ETV7 peaked in metastatic CRC, while ELF1 showed no differences between primary and metastatic CRC tissues. This evidence concerns the gene ELK1 and colorectal carcinoma.