ABCA1 and atherosclerosis: Subsequently, we verified the mechanism of GLSP in the regulation of cholesterol efflux by western blot assay, and the results showed that GLSP promoted the expression of ABCA1 and ABCG1 in peritoneal macrophages from the mice with early and advanced atherosclerosis (Figure 5E-F), which was further supported by the results of immunofluorescence staining of ABCA1 and ABCG1 in aortic root cross-sections (Figure 5G-H).