Examples include p53MVA 182, SGT-53 183, Ad-p53 184, Ad-p53 + CD122/132 181, OBP-702 (a wild-type p53 expressing oncolytic adenovirus), CXCR4-targeted p53 mRNA nanoparticles 185, and APR-246 with anti-PD-1 in several cancer models. This evidence concerns the gene TP53 and cancer.