LTA4H and lung carcinoma: As an essential hydrolase for LTB4 production (Vo, Jang & Jeong, 2018), upregulated LTA4H has been found to be linked with various malignancies, such as colon, esophageal, and lung cancer (Chen et al., 2003a; Chen et al., 2004; Jeong et al., 2009).