MDM2 and neoplasm: Nonetheless, the expression of proteins related to tumor progression, PD-L1, Mdm2, and Mucin-4 demonstrated significant association with greater positivity in patients diagnosed with OSCC OR of 0.12 (95% CI: 0.04 to 0.40; I2 = 36%; p = 0.0006), 0.44 (95% CI: 0.24 to 0.81; I2 = 28%; p = 0.009), and 0.18 (95% CI: 0.04 to 0.86; I2 = 52%; p = 0.03) respectively (Figures 5C–E).