We next found that, in local BC samples, the expression of BIRC2, BIRC5, and WWTR1 was negatively correlated with ZSCAN1, as identified by both immunohistochemistry (Supplementary Figure 5C, P < 0.001 for all) and qRT-PCR (Supplementary Figure 5D, P < 0.001 for all) results. Here, BIRC5 is linked to breast cancer.