Figure 3A shows that the PAO-1 infection stimulates a robust p62 expression, indicating the involvement of xenophagy during the infection. Interestingly, the STING agonist was able to stimulate p62 phosphorylation at serine 403, which is a key marker of autophagy induction, in both WT and ΔF BMDMs (Figure 3B). In addition, we found that 2’,3’ cGAMP promoted LC3I/LC3II conversion (Figure 3A), not only in WT, but also in CF cells that displayed a defective autophagy process. This evidence concerns the gene STING1 and cystic fibrosis.