However, most of the genes showed significant difference expression only in the phase of symptomatic infection, the up-regulated genes mainly included cxcl8a, sting1, ccl19a.1, ccl27b and ccl20a.3, and the down-regulated genes mainly included fractalkine-like, CC motif chemokine 20-like, CC motif chemokine 25-like, CC motif chemokine 3-like, H-2 class II histocompatibility antigen, I-E beta chain-like and chemokine (CXC motif) ligand 32b, duplicate 1 (Table 5). This evidence concerns the gene STING1 and infection.