ABCC4 and Decreased total neutrophil count: It was reported that rs9561778, located in an intron of ABCC4, was associated with cyclophosphamide-induced adverse effects (gastrointestinal toxicity and leukopenia or neutropenia) in patients with breast cancer, and FASTSNP suggested that rs9561778 may be located within transcription factor binding sites or intron enhancer sequences, and is a pathogenic variant affecting gene expression (Low et al., 2009).