On the other hand, DKK3 showed a reciprocal expression to TBX3 (2.20 ± 0.06 in oxyntic glands, 1.75 ± 0.06 in atrophic gastritis, 0.52 ± 0.14 in gastric cancer; Fig. 5A–D). Here, DKK3 is linked to gastric cancer.