Importantly, when supernatants from the MYCN-nonamplified neuroblastoma cell lines SH and AS were tested for their ability to attract immune cell subsets, we observed that migration of monocytes, MDC and PDC induced by these supernatants was abrogated by the addition of anti-CCL2 antibodies, while the modest migration of the other cell subsets was not affected (Fig. 3B). The gene discussed is CCL2; the disease is neuroblastoma.