In our study, we observed little chemokine secretion by neuroblastoma cell lines, except for CCL2, that was secreted by MYCN-nonamplified neuroblastoma cell lines but not by MYCN-amplified neuroblastoma cell lines, suggesting that this chemokine could be involved in the observed differential recruitment of monocytes, MDC and PDC. The gene discussed is CCL2; the disease is neuroblastoma.