FOXO3 and ischemic stroke: Furthermore, rho-miR-125a-5p is related to ischemic stroke and neuronal differentiation (28, 29), and rho-miR-29b-3p targets genes such as FOXO3a and TRAF5 in a cardiac ischemia-reperfusion model to protect cardiomyocytes from endotoxin-induced apoptosis and inflammation (30–32).