As shown in the Fig. 2A, the level of p62 protein did not change significantly during the mid to late phase of infection (from 24 to 32 hpi) when compared to mock cells, but decreased significantly at late stage of the infection (from 36 to 40 hpi), and similarly, the gray scale ratio of p62 protein to β-tubulin bands in CDV-infected Vero cells was much lower than that in negative control cells (Fig. 2B). The gene discussed is SQSTM1; the disease is infection.